Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524934 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL10941977 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL502546 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL11188405 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL10139118 | 0.85 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL260788 | 0.82 | CYP1A2 (0.51) | ALDH1A1TDP1TSHRCYP1A2MAPT | |
| SCHEMBL29367937 | 0.82 | CYP1A2 (0.51) | ALDH1A1TDP1TSHRCYP1A2MAPT | |
| SCHEMBL695556 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL8110785 | 0.81 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 | |
| SCHEMBL30933154 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TDP1TSHRCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LTD (CN) | 2026-02-26 | — | — | US | disclosed |
| US-12275686-B2 | NO donor compound, preparation method thereof, pharmaceutical composition comprising same, and use thereof | SOUTHEAST UNIVERSITY (CN) | 2025-04-15 | — | — | US | disclosed |
| EP-4484409-A1 | NO DONOR COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Southeast University (CN) | 2025-01-01 | — | — | EP | disclosed |
| US-20240409500-A1 | NO DONOR COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | SOUTHEAST UNIVERSITY (CN) | 2024-12-12 | — | — | US | disclosed |
| US-20240317758-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-09-26 | — | — | US | disclosed |
| EP-4320127-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2023235464-A1 | NOVEL EQUILIBRATIVE NUCLEOSIDE TRANSPORTER INHIBITORS AND METHODS OF MAKING AND USING SAME | DUKE UNIVERSITY (US) | 2023-12-07 | — | — | WO | disclosed |
| US-11759527-B2 | Anti-EGFR antibody-drug conjugates | ABBVIE INC. (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2023160344-A1 | NO DONOR COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 东南大学 | 2023-08-31 | — | — | WO | disclosed |
| US-20230265098-A1 | ALKYNE QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN INC. | 2023-08-24 | — | — | US | disclosed |
| EP-2066647-B1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2011-11-09 | — | — | EP | disclosed |
| US-7906522-B2 | 2-aminoquinazoline derivatives | KYOWA HAKKO KIRIN CO., LTD (JP) | 2011-03-15 | — | — | US | disclosed |
| WO-2010122089-A1 | N-PYRAZOLYL CARBOXAMIDES AS CRAC CHANNEL INHIBITORS | GLAXO GROUP LIMITED (GB) | 2010-10-28 | — | — | WO | disclosed |
| US-20100273744-A1 | COMPOUNDS | GORE PAUL MARTIN | 2010-10-28 | — | — | US | disclosed |
| US-20100009978-A1 | Benzoxazoles and Oxazolopyridines Being Useful as Janus Kinases Inhibitors | NOVARTIS AG | 2010-01-14 | — | — | US | disclosed |
| CN-101516860-A | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | disclosed |
| EP-2066647-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | Novartis AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| US-20090137583-A1 | 2-AMINOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| WO-2008031594-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| EP-1878727-A1 | 2-AMINOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137583-A1 | 2-AMINOQUINAZOLINE DERIVATIVES | SLC7A1, SLC38A7, PRMT7 | ALDH1A1 1329/4885TDP1 2847/4885TSHR 581/4885 |
| US-12275686-B2 | NO donor compound, preparation method thereof, pharmaceutical composition comprising same, and use thereof | HIF1A, NOS1, NOS2 | ALDH1A1 497/4885TDP1 985/4885TSHR 4509/4885 |
| US-20100009978-A1 | Benzoxazoles and Oxazolopyridines Being Useful as Janus Kinases Inhibitors | JAK2, JAK3, JAK1 | ALDH1A1 1245/4885TDP1 3043/4885TSHR 1681/4885 |
| US-20260055108-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | CBR1, CNR1, CBR3 | ALDH1A1 1308/4885TDP1 3850/4885TSHR 98/4885 |
| US-11759527-B2 | Anti-EGFR antibody-drug conjugates | EGFR, ERBB2, ERBB3 | ALDH1A1 1828/4885TDP1 3514/4885TSHR 1240/4885 |
| US-20230265098-A1 | ALKYNE QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2 | ERBB2, ERBB3, CHEK2 | ALDH1A1 2707/4885TDP1 2584/4885TSHR 1389/4885 |
| US-20240317758-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | ALDH1A1 4225/4885TDP1 635/4885TSHR 4611/4885 |
| US-20240409500-A1 | NO DONOR COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | HIF1A, NOS1, NOS2 | ALDH1A1 497/4885TDP1 985/4885TSHR 4509/4885 |
| US-20100273744-A1 | COMPOUNDS | LTC4S, HRH4, HRH2 | ALDH1A1 447/4885TDP1 4000/4885TSHR 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.