Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR1D | P28221 | 5/20 | 0.54 |
| ▸ | HTR1B | P28222 | 5/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957729 | 0.89 | MPO (0.61) | HTR1AHTR1DHTR1BHTR2ASLC6A4 | |
| SCHEMBL6951363 | 0.89 | HTR1A (0.55) | HTR1AHTR1DHTR1BMEN1LMNA | |
| SCHEMBL6952634 | 0.89 | MPO (0.61) | HTR1AHTR1DHTR1BHTR2ASLC6A4 | |
| SCHEMBL6958552 | 0.89 | MPO (0.61) | HTR1AHTR1DHTR1BHTR2ASLC6A4 | |
| SCHEMBL6950516 | 0.88 | HTR1A (0.56) | HTR1AHTR1DHTR1BCARM1PRMT6 | |
| SCHEMBL6954556 | 0.88 | HTR1A (0.60) | HTR1AHTR1BHTR2ASLC6A4 | |
| SCHEMBL6954396 | 0.87 | HTR1D (0.50) | HTR1AHTR1DHTR1BSLC6A4 | |
| SCHEMBL6957708 | 0.86 | SLC6A4 (0.61) | HTR1ASLC6A4 | |
| SCHEMBL6954897 | 0.86 | SLC6A4 (0.61) | HTR1ASLC6A4 | |
| SCHEMBL6947723 | 0.86 | KDM4E (0.58) | HTR1AHTR1DHTR1BKMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |