Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375896 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL7417406 | 0.82 | ALDH1A1 (0.70) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL7419641 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL7422213 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL3453497 | 0.77 | CRHBP (0.70) | ALDH1A1CRHBPCRHR2LMNAMAPT | |
| SCHEMBL7416266 | 0.76 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8103391 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2GAA | |
| SCHEMBL10373835 | 0.75 | ATM (0.54) | ALDH1A1CRHBPCRHR2MAPTSMN1; SMN2 | |
| SCHEMBL7426611 | 0.74 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL7377964 | 0.73 | POLB (0.56) | ALDH1A1CRHBPCRHR2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |