Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375896 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL7417406 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL8103391 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL6957845 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AMEN1CRHBP | |
| SCHEMBL3532473 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL7426611 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL1548167 | 0.77 | ATM (0.55) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL9402668 | 0.74 | KMT2A (0.56) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL7418231 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL6607753 | 0.74 | SMN1; SMN2 (0.57) | ALDH1A1KMT2AHTTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885205-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0885205-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5780480-A | THROMBOLYTIC AGENTS, ANTICOAGULANTS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1997031910-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-09-04 | — | — | WO | disclosed |