Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955990 | 0.84 | NOD2 (0.73) | MCL1NOD2NOD1ALOX5PPARG | |
| SCHEMBL1272442 | 0.84 | ACLY (0.48) | NOD2NOD1PPARGPPARDMETAP2 | |
| SCHEMBL16794402 | 0.83 | NOD1 (0.71) | MCL1NOD2NOD1ALOX5CCR2 | |
| SCHEMBL10003058 | 0.83 | NOD2 (0.47) | MCL1NOD2NOD1ALOX5PPARG | |
| SCHEMBL6954079 | 0.81 | ACLY (0.56) | MCL1CCR2PPARGPPARDPPARA | |
| SCHEMBL20465155 | 0.79 | PPARG (0.42) | MCL1NOD2NOD1ALOX5PPARG | |
| SCHEMBL15882629 | 0.79 | NOD1 (0.50) | MCL1NOD2NOD1ALOX5CCR2 | |
| SCHEMBL28411702 | 0.79 | ACLY (0.60) | PPARGPPARAACLYAGTR1TP53 | |
| SCHEMBL10003655 | 0.78 | ALOX5 (0.43) | MCL1NOD2NOD1ALOX5PPARG | |
| SCHEMBL10003661 | 0.78 | ALOX5 (0.43) | MCL1NOD2NOD1ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001935-B1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | EP | claimed |