Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989000 | 0.88 | DRD1 (0.39) | DRD1LIPEMAPK1PRMT5SPR | |
| SCHEMBL6969253 | 0.85 | DRD1 (0.40) | DRD1KDM4EALDH1A1KMT2A | |
| SCHEMBL6957781 | 0.83 | DRD1 (0.39) | DRD1LIPEMAPK1SPRPRCP | |
| SCHEMBL6995013 | 0.83 | DRD1 (0.39) | DRD1LIPEMAPK1SPRPRCP | |
| SCHEMBL7000740 | 0.83 | DRD1 (0.39) | DRD1LIPEMAPK1SPRPRCP | |
| Hydrochloric Acid SCHEMBL6958005 | 0.82 | KCNH3 (0.35) | KDM4EALDH1A1MEN1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL6962670 | 0.80 | MAP4K1 (0.35) | KDM4EALDH1A1MEN1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL6965281 | 0.79 | KCNH3 (0.40) | KDM4EALDH1A1MEN1HPGDMAPK1 | |
| SCHEMBL6966656 | 0.77 | CHRM3 (0.46) | KDM4EALDH1A1MEN1HPGDHTT | |
| Hydrochloric Acid SCHEMBL6967084 | 0.76 | GALR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |