Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997338 | 0.86 | PDE4A (0.46) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6966650 | 0.81 | CHRM3 (0.49) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7686680 | 0.79 | PDE4A (0.43) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL6962264 | 0.79 | CHRM3 (0.42) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6958205 | 0.77 | DRD1 (0.37) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL6966987 | 0.77 | KCNH3 (0.42) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8117433 | 0.76 | FAAH (0.35) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8109958 | 0.76 | CHRM3 (0.35) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7960352 | 0.75 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6969212 | 0.74 | CHRM3 (0.39) | CHRM3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |