SCHEMBL6958232

SCHEMBL6958232

Fc1ccccc1CCNC(=S)Nc1nccs1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.74
RAB9A P51151 6/20 0.74
KDM4E B2RXH2 3/20 0.74
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
GAA P10253 4/20 0.52
HTT P42858 4/20 0.52
ALDH1A1 P00352 3/20 0.52
NFKB1 P19838 2/20 0.52
LMNA P02545 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52
THPO P40225 1/20 0.52
MTOR P42345 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL8684815 0.94 NPC1 (0.67) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6961866 0.86 NPC1 (0.55) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL29353571 0.86 RAB9A (0.55) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6957663 0.86 RAB9A (0.55) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6953553 0.85 NPC1 (0.54) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6957979 0.85 RAB9A (0.54) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6955476 0.85 KDM4E (0.59) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6961594 0.85 RAB9A (0.54) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL29352046 0.85 NPC1 (0.54) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL6958503 0.84 RAB9A (0.54) NPC1RAB9AKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875053-A Low-odor flame-retardant polyurethane foam material for vehicle-mounted refrigerator and preparation method thereof 山东一诺威新材料有限公司 2025-04-25 CN claimed
CN-119119422-A High-water-absorption polyvinyl alcohol-single-component polyurethane water shutoff reinforcement material and preparation method thereof 郑州大学 2024-12-13 CN claimed
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-07-25 US claimed
CN-118271949-A Composition for spraying polyurethane hard foam layer and polyurethane hard foam layer 廊坊华宇创新科技有限公司 2024-07-02 CN claimed
US-20250372258-A1 COMPUTATIONAL FRAMEWORK FOR ENHANCING A SIGNAL-TO-NOISE RATIO (SNR) IN PROCESSING NOISY READ SIGNALS THE BROAD INSTITUTE, INC. (US) 2025-12-04 US disclosed
WO-2025245123-A1 METHODS AND MATERIALS FOR ASSESSING CANCER TREATMENTS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-11-27 WO disclosed
CN-119875053-A Low-odor flame-retardant polyurethane foam material for vehicle-mounted refrigerator and preparation method thereof 山东一诺威新材料有限公司 2025-04-25 CN disclosed
US-20250003976-A1 ANTIBODIES TARGETING PHOSPHORYLATED SEVEN-TRANSMEMBRANE RECEPTORS 7TM ANTIBODIES GMBH (DE) 2025-01-02 US disclosed
CN-119119422-A High-water-absorption polyvinyl alcohol-single-component polyurethane water shutoff reinforcement material and preparation method thereof 郑州大学 2024-12-13 CN disclosed
CN-115894571-B Single-core metal platinum complex green phosphorescence luminescent material and application thereof in organic electroluminescent device 吉林大学 2024-09-10 CN disclosed
CN-118271949-A Composition for spraying polyurethane hard foam layer and polyurethane hard foam layer 廊坊华宇创新科技有限公司 2024-07-02 CN disclosed
CN-117903396-A High-flame-retardance combined polyether for adhesive for smart home and application of high-flame-retardance combined polyether 山东一诺威新材料有限公司 2024-04-19 CN disclosed
CN-115370561-A Air compressor controller and control method thereof 天津森普捷电子有限公司 2022-11-22 CN disclosed
US-11230599-B2 Tumor mutational load MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-01-25 US disclosed
EP-0540143-B1 Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 2003-02-05 EP disclosed
US-5714503-A Compounds and methods for inhibition of HIV and related viruses MEDIVIR AB (SE) 1998-02-03 US disclosed
US-5658907-A THIOUREA VIRICIDES MEDIVIR A/B (SE) 1997-08-19 US disclosed
US-5593993-A VIRICIDES FOR HTLV TREATMENT OF AIDS MEDIVIR AB (SE) 1997-01-14 US disclosed
EP-0540143-A2 Compounds and methods for inhibition of HIV and related viruses Medivir Aktiebolag (SE) 1993-05-05 EP disclosed
WO-1993003022-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1993-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240251654-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EFNA1, EML4 NPC1 2452/4885RAB9A 2013/4885KDM4E 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.