Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959831 | 0.86 | LMNA (0.62) | GAAMAPTHPGDLMNAMEN1 | |
| SCHEMBL6958110 | 0.85 | ALOX12 (0.52) | GAAMAPTHPGDQPCTLMNA | |
| SCHEMBL9579768 | 0.84 | NPC1 (0.44) | GAAMAPTHPGDLMNAMEN1 | |
| SCHEMBL6964723 | 0.83 | ALDH1A1 (0.54) | GAAMAPTHPGDQPCTLMNA | |
| SCHEMBL6963917 | 0.83 | RAB9A (0.56) | GAAMAPTHPGDLMNAMEN1 | |
| SCHEMBL2161633 | 0.82 | CHRM2 (0.55) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6960260 | 0.82 | RAB9A (0.60) | GAAMAPTHPGDQPCTLMNA | |
| SCHEMBL6952474 | 0.81 | MEN1 (0.53) | GAAMAPTHPGDQPCTLMNA | |
| SCHEMBL6959257 | 0.81 | MEN1 (0.50) | GAAMAPTHPGDQPCTLMNA | |
| SCHEMBL6958534 | 0.81 | ALDH1A1 (0.45) | GAAMAPTQPCTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |