Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 6/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TRHR | P34981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966152 | 0.96 | KLK7 (0.34) | KLK7TRHDEPABPC1HDAC8SCN9A | |
| SCHEMBL6965676 | 0.91 | PABPC1 (0.41) | PABPC1HDAC8SCN9AP2RX7 | |
| SCHEMBL6965678 | 0.91 | PABPC1 (0.41) | PABPC1HDAC8SCN9AP2RX7 | |
| SCHEMBL6963909 | 0.87 | KLK7 (0.40) | KLK7PABPC1GHSRSCN9AP2RX7 | |
| SCHEMBL6963911 | 0.87 | KLK7 (0.40) | KLK7PABPC1GHSRSCN9AP2RX7 | |
| SCHEMBL6967714 | 0.86 | PABPC1 (0.41) | PABPC1HDAC8SCN9AP2RX7 | |
| SCHEMBL6967718 | 0.86 | PABPC1 (0.41) | PABPC1HDAC8SCN9AP2RX7 | |
| SCHEMBL6962443 | 0.86 | KLK7 (0.35) | KLK7TRHDEPABPC1SCN9ATRHR | |
| SCHEMBL6968593 | 0.85 | SCN9A (0.33) | PABPC1GHSRSCN9AP2RX7 | |
| SCHEMBL6963915 | 0.85 | SCN9A (0.36) | PABPC1GHSRSCN9AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |