Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 4/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | CDC25B | P30305 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963911 | 1.00 | KLK7 (0.40) | KLK7KLK5PPARACTSSP2RX7 | |
| SCHEMBL6957715 | 0.95 | KLK7 (0.40) | KLK7KLK5PPARACTSSP2RX7 | |
| SCHEMBL6957710 | 0.95 | KLK7 (0.40) | KLK7KLK5PPARACTSSP2RX7 | |
| SCHEMBL6965676 | 0.93 | PABPC1 (0.41) | CTSSP2RX7PABPC1SCN9A | |
| SCHEMBL6965678 | 0.93 | PABPC1 (0.41) | CTSSP2RX7PABPC1SCN9A | |
| SCHEMBL6968593 | 0.89 | SCN9A (0.33) | P2RX7PABPC1GHSRSCN9A | |
| SCHEMBL6963915 | 0.89 | SCN9A (0.36) | P2RX7PABPC1GHSRSCN9A | |
| SCHEMBL6967714 | 0.88 | PABPC1 (0.41) | CTSSP2RX7PABPC1SCN9A | |
| SCHEMBL6967718 | 0.88 | PABPC1 (0.41) | CTSSP2RX7PABPC1SCN9A | |
| SCHEMBL6963190 | 0.88 | SCN9A (0.39) | PABPC1GHSRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |