Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17108385 | 0.81 | ANPEP (0.42) | ANPEPCES2CES1ESR1ESR2 | |
| SCHEMBL533709 | 0.78 | CYP11B1 (0.46) | CES2CES1 | |
| SCHEMBL1525706 | 0.78 | CES2 (0.45) | ANPEPCES2CES1ESR1ESR2 | |
| SCHEMBL534148 | 0.77 | NOTUM (0.35) | ESR2 | |
| SCHEMBL9646722 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL2872756 | 0.75 | — | — | |
| SCHEMBL1510357 | 0.74 | AKR1C2 (0.43) | AKR1C2AKR1C1 | |
| SCHEMBL27637511 | 0.74 | SLC6A4 (0.33) | ESR1ESR2 | |
| SCHEMBL196583 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL3006080 | 0.74 | ALDH1A1 (0.50) | ANPEPAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603088-A | Aromatic aldehyde Schiff base based on amino acid ethyl ester and application thereof in asymmetric alkylation | 广东工业大学 | 2024-02-27 | — | — | CN | claimed |
| CN-114768866-B | Chiral deuterated Maruoka phase transfer catalyst, preparation method thereof and application thereof in asymmetric catalytic reaction | 广东工业大学 | 2023-10-17 | — | — | CN | claimed |
| CN-114768866-A | Chiral deuterated Maruoka phase transfer catalyst, preparation method thereof and application thereof in asymmetric catalytic reaction | 广东工业大学 | 2022-07-22 | — | — | CN | claimed |
| EP-3558975-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| US-8362001-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-29 | — | — | US | claimed |
| EP-2421848-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| US-20100331300-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-30 | — | — | US | claimed |
| WO-2010124119-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |
| CN-117603088-A | Aromatic aldehyde Schiff base based on amino acid ethyl ester and application thereof in asymmetric alkylation | 广东工业大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-114768866-B | Chiral deuterated Maruoka phase transfer catalyst, preparation method thereof and application thereof in asymmetric catalytic reaction | 广东工业大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-114768866-A | Chiral deuterated Maruoka phase transfer catalyst, preparation method thereof and application thereof in asymmetric catalytic reaction | 广东工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-107141313-A | Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified | 信越化学工业株式会社 | 2017-09-08 | — | — | CN | disclosed |
| CN-105601917-A | Soluble polyimide, and preparation method thereof | JIANGSU MO OPTO-ELECTRONIC MAT CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-103848859-A | Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same | SHINETSU CHEMICAL CO | 2014-06-11 | — | — | CN | disclosed |
| US-8362001-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-29 | — | — | US | disclosed |
| EP-2421848-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | disclosed |
| US-20100331300-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-30 | — | — | US | disclosed |
| WO-2010124119-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | disclosed |
| EP-0929508-B1 | LIQUID CRYSTALLINE (E,E)-BUTADIENE COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2002-03-20 | — | — | EP | disclosed |
| US-6333082-B1 | USEFUL IN SUPER TWISTED NEMATIC LIQUID CRYSTAL DISPLAYS | QINETIQ LTD (GB) | 2001-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331300-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | ANPEP 482/4885CES2 39/4885CES1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.