Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8084745 | 0.91 | CYP11B2 (0.37) | CYP11B2ADRA2AHTR2CHTR2AHTR2B | |
| Fumaric Acid SCHEMBL8084750 | 0.91 | CYP11B2 (0.37) | CYP11B2ADRA2AHTR2CHTR2AHTR2B | |
| SCHEMBL6954207 | 0.81 | ADRA2A (0.59) | ADRA2AHTR2CHTR2A | |
| SCHEMBL6949362 | 0.78 | ADRA2A (0.56) | ADRA2AHTR2CHTR2AHTR2B | |
| SCHEMBL6958891 | 0.78 | ADRA2A (0.56) | ADRA2AHTR2CHTR2AHTR2B | |
| SCHEMBL6949759 | 0.78 | ADRA2A (0.56) | ADRA2AHTR2CHTR2AHTR2B | |
| SCHEMBL6960180 | 0.77 | ADRA2A (0.37) | ADRA2A | |
| Fumaric Acid SCHEMBL8093365 | 0.76 | ADRA2A (0.36) | ADRA2A | |
| Fumaric Acid SCHEMBL8093372 | 0.76 | ADRA2A (0.36) | ADRA2A | |
| SCHEMBL6952658 | 0.74 | ADRA2A (0.40) | ADRA2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |