Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8090876 | 0.90 | MCHR1 (0.33) | ADRA2AMCHR1 | |
| SCHEMBL6954399 | 0.90 | ADRA2A (0.42) | ADRA2A | |
| SCHEMBL6949759 | 0.81 | ADRA2A (0.56) | ADRA2A | |
| SCHEMBL6958891 | 0.81 | ADRA2A (0.56) | ADRA2A | |
| SCHEMBL6949362 | 0.81 | ADRA2A (0.56) | ADRA2A | |
| Fumaric Acid SCHEMBL8093372 | 0.81 | ADRA2A (0.36) | ADRA2A | |
| Fumaric Acid SCHEMBL8093365 | 0.81 | ADRA2A (0.36) | ADRA2A | |
| SCHEMBL6954207 | 0.77 | ADRA2A (0.59) | ADRA2A | |
| SCHEMBL6958856 | 0.77 | CYP11B2 (0.40) | ADRA2A | |
| SCHEMBL6959269 | 0.74 | ADRA2A (0.42) | ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010693-B1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-1010693-A1 | Imidazoline derivatives, preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |