Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951823 | 0.84 | RAB9A (0.64) | ALDH1A1SMN1; SMN2LMNAALOX12HPGD | |
| SCHEMBL8893941 | 0.82 | MAPT (0.65) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL8891868 | 0.81 | MAPT (0.81) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL6964080 | 0.80 | SCD (0.54) | ALDH1A1SMN1; SMN2LMNAALOX12HPGD | |
| SCHEMBL8892058 | 0.79 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2LMNAALOX12HPGD | |
| SCHEMBL9988695 | 0.78 | ACP1 (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDMAPT | |
| SCHEMBL6962564 | 0.75 | MAPT (0.67) | ALDH1A1SMN1; SMN2LMNAALOX12MAPT | |
| SCHEMBL6959560 | 0.75 | MAPT (0.51) | ALDH1A1SMN1; SMN2LMNAALOX12MAPT | |
| SCHEMBL6963487 | 0.75 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAALOX12HPGD | |
| SCHEMBL6958936 | 0.75 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNAALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |