Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972651 | 0.91 | ALDH1A1 (0.41) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6964164 | 0.90 | NPSR1 (0.46) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6959155 | 0.89 | LMNA (0.50) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6964907 | 0.89 | NPSR1 (0.45) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6960127 | 0.85 | NPSR1 (0.49) | NPSR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6968111 | 0.80 | ALDH1A1 (0.43) | NPSR1MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL6955643 | 0.80 | L3MBTL1 (0.46) | NPSR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6970362 | 0.80 | AVPR1A (0.49) | ALDH1A1PDCD1CD274MAPT | |
| SCHEMBL6964781 | 0.79 | L3MBTL1 (0.46) | NPSR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6960505 | 0.79 | LMNA (0.52) | NPSR1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |