Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959155 | 0.91 | LMNA (0.50) | ALDH1A1THRBPOLBCYP2C19LMNA | |
| SCHEMBL6959345 | 0.91 | PDE4A (0.45) | ALDH1A1POLBCYP2C19MEN1RAB9A | |
| SCHEMBL6968111 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CYP2C19MEN1RAB9AKMT2A | |
| SCHEMBL6970661 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP2C19MEN1RAB9AKMT2A | |
| SCHEMBL6969398 | 0.86 | ALDH1A1 (0.42) | ALDH1A1THRBPOLBCYP2C19MEN1 | |
| SCHEMBL6969459 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP2C19MEN1RAB9AKMT2A | |
| SCHEMBL6971802 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1POLBMEN1RAB9AKMT2A | |
| SCHEMBL6960505 | 0.81 | LMNA (0.52) | ALDH1A1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL6962852 | 0.81 | CA1 (0.43) | ALDH1A1THRBPOLBCYP2C19MEN1 | |
| SCHEMBL6964164 | 0.81 | NPSR1 (0.46) | ALDH1A1MEN1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |