SCHEMBL6959536 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	9/20	0.51

▸	MMP3	P08254	9/20	0.51

▸	MMP1	P03956	2/20	0.47

▸	MMP9	P14780	2/20	0.47

▸	MMP14	P50281	2/20	0.47

▸	PRMT5	O14744	1/20	0.33

▸	WDR77	Q9BQA1	1/20	0.33

▸	ALDH1A1	P00352	2/20	0.31

▸	USP5	P45974	1/20	0.30

▸	DHODH	Q02127	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6973195	0.92	MMP2 (0.53)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6960736	0.88	MMP3 (0.49)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6970701	0.88	MMP2 (0.60)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6434175	0.86	MMP2 (0.54)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6964791	0.84	MMP2 (0.51)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6437467	0.81	MMP2 (0.51)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433679	0.81	MMP2 (0.51)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433156	0.81	MMP2 (0.51)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6959909	0.79	MMP2 (0.51)	MMP2MMP3MMP1MMP9MMP14
SCHEMBL6971910	0.79	MMP2 (0.63)	MMP2MMP3MMP1MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1181017-B1	METALLOPROTEASE INHIBITORS	PFIZER LTD (GB)	2003-04-16	—	—	EP	claimed