Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598733 | 0.90 | KMT2A (0.69) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| Ammonia Solution, Strong SCHEMBL27830689 | 0.88 | KMT2A (0.67) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL2914808 | 0.86 | KMT2A (0.64) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL6959479 | 0.85 | MMP8 (0.68) | KMT2AMMP8SRCMEN1TSHR | |
| SCHEMBL11031397 | 0.84 | KMT2A (0.62) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL2227571 | 0.84 | KMT2A (0.62) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL11679477 | 0.82 | KMT2A (0.60) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL13158250 | 0.81 | KMT2A (0.58) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL28474562 | 0.81 | MMP8 (0.73) | KMT2AMMP8ALDH1A1MEN1GLS | |
| SCHEMBL17295202 | 0.79 | KMT2A (0.56) | KMT2AMMP8ALDH1A1SRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |