Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598733 | 0.88 | KMT2A (0.69) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| Ammonia Solution, Strong SCHEMBL27830689 | 0.86 | KMT2A (0.67) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL5458091 | 0.85 | MMP8 (0.66) | KMT2AMMP8SRCMEN1SLC6A3 | |
| SCHEMBL2914808 | 0.84 | KMT2A (0.64) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL11031397 | 0.82 | KMT2A (0.62) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL6959628 | 0.82 | KMT2A (0.62) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL2227571 | 0.82 | KMT2A (0.62) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL1375360 | 0.81 | SRC (0.64) | KMT2AALDH1A1SRCLMNA | |
| SCHEMBL11218538 | 0.80 | KMT2A (0.46) | KMT2AMMP8ALDH1A1SRCMEN1 | |
| SCHEMBL11601985 | 0.80 | SRC (0.44) | KMT2AMMP8ALDH1A1SRCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005074-A | Process for cleaving an imido side chain from penicillins and cephalosporins | ELI LILLY AND COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001239-A | CEPHALOSPORIN CLEAVAGE PROCESS | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3994888-A | Cephalosporin cleavage process | ELI LILLY AND COMPANY (US) | 1976-11-30 | — | — | US | disclosed |