Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911579 | 0.90 | ALDH1A1 (0.39) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL10913091 | 0.88 | MAPT (0.43) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL6956139 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1F2RL3 | |
| SCHEMBL10923317 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL10913839 | 0.82 | HRH2 (0.40) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL10911009 | 0.81 | TDP1 (0.39) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL10913633 | 0.81 | LMNA (0.40) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL29351076 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL744307 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL11038529 | 0.77 | HSD17B10 (0.33) | MAPTSMN1; SMN2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | claimed |