Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914742 | 0.88 | HRH2 (0.34) | ALDH1A1MAPTTP53MAOBMEN1 | |
| SCHEMBL6959645 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTNPSR1TP53NPC1 | |
| SCHEMBL11006059 | 0.84 | SMN1; SMN2 (0.39) | ALDH1A1MAPTNPSR1TP53NPC1 | |
| SCHEMBL10921450 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2APDE4B | |
| SCHEMBL10748490 | 0.76 | TDP2 (0.38) | ALDH1A1MAPTNPSR1TP53NPC1 | |
| SCHEMBL10911579 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTNPSR1TP53NPC1 | |
| SCHEMBL10913091 | 0.73 | MAPT (0.43) | ALDH1A1MAPTNPSR1NPC1RAB9A | |
| SCHEMBL10970619 | 0.72 | ALDH1A1 (0.38) | ALDH1A1MAPTMAOBMEN1KMT2A | |
| SCHEMBL6956139 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10923622 | 0.71 | LDHA (0.39) | ALDH1A1KMT2AHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088938-B1 | USE OF PYRIDINE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS WITH AN ANTIHYPOXEMIA AND ISCHEMIA-PROTECTIVE ACTIVITY | BAYER AG (DE) | 1986-04-30 | — | — | EP | disclosed |