Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961528 | 0.90 | HTR7 (0.48) | HTR7KITMAPTALDH1A1RECQL | |
| SCHEMBL6956776 | 0.83 | MAP4K1 (0.42) | MAPTALDH1A1MAP4K1GFERDRD3 | |
| SCHEMBL6956631 | 0.83 | MAPT (0.44) | MAPTALDH1A1RECQLTDP1MAP4K1 | |
| SCHEMBL6952935 | 0.82 | MAP4K1 (0.41) | HTR7ALDH1A1MAP4K1HPGD | |
| SCHEMBL6966887 | 0.82 | KIT (0.47) | HTR7KITMAPTALDH1A1RECQL | |
| SCHEMBL6966395 | 0.81 | FYN (0.43) | HTR7MAPTALDH1A1TDP1MAP4K1 | |
| SCHEMBL6959295 | 0.80 | MEN1 (0.42) | MAPTALDH1A1MAP4K1DRD3DRD2 | |
| SCHEMBL6959773 | 0.80 | KIT (0.38) | HTR7KITMAPTALDH1A1RECQL | |
| SCHEMBL6966641 | 0.79 | TP53 (0.41) | HTR7MAPTALDH1A1MAP4K1RAB9A | |
| SCHEMBL6955333 | 0.79 | POLB (0.42) | HTR7MAPTALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | claimed |
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-6043246-A | Urea derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |