Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959295 | 0.92 | MEN1 (0.42) | MAP4K1MAPTSMN1; SMN2HTR1AMEN1 | |
| SCHEMBL6967175 | 0.89 | KDM4E (0.38) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6956631 | 0.88 | MAPT (0.44) | TP53MAP4K1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6956776 | 0.88 | MAP4K1 (0.42) | TP53MAP4K1MAPTSMN1; SMN2HTR1A | |
| SCHEMBL6955333 | 0.88 | POLB (0.42) | TP53MAPTSMN1; SMN2HTR1ANPC1 | |
| SCHEMBL6968659 | 0.85 | MAP4K1 (0.46) | MAP4K1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6961353 | 0.84 | MAPT (0.40) | TP53MAPTSMN1; SMN2HTR1ANPC1 | |
| SCHEMBL6961941 | 0.84 | MAPT (0.42) | MAPTSMN1; SMN2HTR1AKDM4EMEN1 | |
| SCHEMBL6961528 | 0.83 | HTR7 (0.48) | TP53MAP4K1MAPTRAB9AKDM4E | |
| SCHEMBL6963927 | 0.81 | ABCG2 (0.45) | MAPTSMN1; SMN2HTR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |