Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 4/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959295 | 0.89 | MEN1 (0.42) | MAP4K1ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL6952935 | 0.89 | MAP4K1 (0.41) | MAP4K1ALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL6966641 | 0.88 | TP53 (0.41) | MAP4K1ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL6967175 | 0.86 | KDM4E (0.38) | ALDH1A1KDM4EGFERMAPTTSHR | |
| SCHEMBL6956631 | 0.85 | MAPT (0.44) | MAP4K1ALDH1A1KDM4EMAPTTP53 | |
| SCHEMBL6959768 | 0.83 | HTR7 (0.38) | MAP4K1ALDH1A1KDM4EGFERMAPT | |
| SCHEMBL6968659 | 0.82 | MAP4K1 (0.46) | MAP4K1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL6955333 | 0.81 | POLB (0.42) | ALDH1A1KDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL6961941 | 0.81 | MAPT (0.42) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL6961528 | 0.81 | HTR7 (0.48) | MAP4K1ALDH1A1KDM4EGFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |