Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 9/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956776 | 0.89 | MAP4K1 (0.42) | MAP4K1PDE3BPDE3AALDH1A1HPGD | |
| SCHEMBL6955333 | 0.87 | POLB (0.42) | HTR7PDE3BPDE3ATACR3ALDH1A1 | |
| SCHEMBL6966146 | 0.85 | ABCG2 (0.43) | HTR7PDE3BPDE3ATACR3ALDH1A1 | |
| SCHEMBL6963927 | 0.85 | ABCG2 (0.45) | HTR7ALDH1A1 | |
| SCHEMBL6966887 | 0.84 | KIT (0.47) | HTR7ALDH1A1HPGD | |
| SCHEMBL6959295 | 0.84 | MEN1 (0.42) | MAP4K1PDE3BPDE3ATACR3ALDH1A1 | |
| SCHEMBL6959768 | 0.82 | HTR7 (0.38) | MAP4K1HTR7ALDH1A1HPGD | |
| SCHEMBL6966641 | 0.81 | TP53 (0.41) | MAP4K1HTR7ALDH1A1HPGD | |
| SCHEMBL6961941 | 0.81 | MAPT (0.42) | HTR7PDE3BPDE3ATACR3ALDH1A1 | |
| SCHEMBL6961528 | 0.80 | HTR7 (0.48) | MAP4K1HTR7ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |