Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626816 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL8625977 | 0.99 | KDM4E (0.40) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL28129243 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTTMAPTHRH3 | |
| SCHEMBL7504135 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EHTTMAPTHRH3 | |
| SCHEMBL8624515 | 0.80 | CES1 (0.43) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL8624518 | 0.80 | CES1 (0.43) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL7783261 | 0.75 | CES1 (0.40) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL8623432 | 0.74 | CES1 (0.39) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 | |
| SCHEMBL28465551 | 0.74 | CNR2 (0.35) | ALDH1A1KDM4EHTTMAPTHRH3 | |
| SCHEMBL8623299 | 0.73 | CES1 (0.38) | ALDH1A1KDM4EHTTSMN1; SMN2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| CN-109939114-A | Meropenem intermediate related compound and its application in anti-tumor drug | 江苏汉阔生物有限公司 | 2019-06-28 | — | — | CN | disclosed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5792861-A | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5703234-A | CHEMICAL INTERMEDIATE FOR 1-METHYLCARBAPENEM ANTIBIOTICS | TANABE SEIYAKU CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0632037-B1 | Process for the production of 4-substituted azetidinone derivatives | TANABE SEIYAKU CO (JP) | 1997-10-01 | — | — | EP | disclosed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0635488-A2 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0632037-A1 | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |