Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 9/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624515 | 0.86 | CES1 (0.43) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8624518 | 0.81 | CES1 (0.43) | CES1KDM4EHTTSMN1; SMN2ASAH1 | |
| SCHEMBL8625977 | 0.76 | KDM4E (0.40) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8626816 | 0.75 | ALDH1A1 (0.41) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8623432 | 0.75 | CES1 (0.39) | CES1KDM4EHTTSMN1; SMN2POLB | |
| SCHEMBL6959879 | 0.75 | ALDH1A1 (0.41) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14414191 | 0.74 | KMT2A (0.35) | CES1KDM4EHTTASAH1ALDH1A1 | |
| SCHEMBL8623299 | 0.74 | CES1 (0.38) | CES1KDM4EHTTSMN1; SMN2POLB | |
| SCHEMBL7783218 | 0.65 | KDM4E (0.35) | KDM4EHTTPKMPOLBALDH1A1 | |
| SCHEMBL7512827 | 0.65 | ALDH1A1 (0.47) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7097381-A | — | — | None | — | — | JP | disclosed |
| EP-0635488-B1 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-5703234-A | CHEMICAL INTERMEDIATE FOR 1-METHYLCARBAPENEM ANTIBIOTICS | TANABE SEIYAKU CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5550229-A | REACTING SPECIFIED ALKANAMIDE WITH SUBSTITUTED AZETIDINONE IN PRESENCE OF BASE | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| JP-H0797381-A | NEW PRODUCTION METHOD OF AZETIDINONE COMPOUND AND NEW RAW MATERIAL COMPOUND THEREFOR | TANABE SEIYAKU CO LTD | 1995-04-11 | — | — | JP | disclosed |
| EP-0635488-A2 | Novel process for preparing azetidinone compound and novel starting compound therefor | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-25 | — | — | EP | disclosed |