Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783261 | 0.86 | CES1 (0.40) | CES1HTTKDM4ESMN1; SMN2ELANE | |
| SCHEMBL8624518 | 0.85 | CES1 (0.43) | CES1HTTKDM4ESMN1; SMN2ELANE | |
| SCHEMBL8623432 | 0.82 | CES1 (0.39) | CES1HTTKDM4ESMN1; SMN2ELANE | |
| SCHEMBL8625977 | 0.81 | KDM4E (0.40) | CES1HTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8626816 | 0.80 | ALDH1A1 (0.41) | CES1HTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6959879 | 0.80 | ALDH1A1 (0.41) | CES1HTTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8623299 | 0.79 | CES1 (0.38) | CES1HTTKDM4ESMN1; SMN2ELANE | |
| SCHEMBL14414191 | 0.70 | KMT2A (0.35) | CES1HTTKDM4EALDH1A1MAPT | |
| SCHEMBL7335823 | 0.67 | CES1 (0.66) | CES1HTTKDM4ESMN1; SMN2ELANE | |
| SCHEMBL15233290 | 0.66 | SIGMAR1 (0.60) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792861-A | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0632037-B1 | Process for the production of 4-substituted azetidinone derivatives | TANABE SEIYAKU CO (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0632037-A1 | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |