Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624518 | 0.81 | CES1 (0.43) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8623432 | 0.81 | CES1 (0.39) | CES1KDM4EHTTSMN1; SMN2KMT2A | |
| SCHEMBL8624515 | 0.79 | CES1 (0.43) | CES1KDM4EHTTSMN1; SMN2KMT2A | |
| SCHEMBL7783261 | 0.74 | CES1 (0.40) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8625977 | 0.74 | KDM4E (0.40) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6959879 | 0.73 | ALDH1A1 (0.41) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8626816 | 0.73 | ALDH1A1 (0.41) | CES1KDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14414191 | 0.68 | KMT2A (0.35) | CES1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL28129243 | 0.62 | ALDH1A1 (0.39) | KDM4EHTTKMT2AALDH1A1MAPT | |
| SCHEMBL7504135 | 0.62 | ALDH1A1 (0.39) | KDM4EHTTKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792861-A | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0632037-B1 | Process for the production of 4-substituted azetidinone derivatives | TANABE SEIYAKU CO (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0632037-A1 | Process for the production of 4-substituted azetidinone derivative | TANABE SEIYAKU CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |