Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734135 | 0.83 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL4953691 | 0.77 | — | — | |
| SCHEMBL712181 | 0.76 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL6959896 | 0.74 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL6955782 | 0.73 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL21306959 | 0.70 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TSHR | |
| SCHEMBL3136565 | 0.69 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL6969487 | 0.69 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1TP53TSHR | |
| SCHEMBL6955786 | 0.69 | L3MBTL1 (0.42) | L3MBTL1 | |
| SCHEMBL1563693 | 0.67 | CRBN (0.41) | L3MBTL1ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |