Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966237 | 0.89 | PHGDH (0.56) | KMT2AMEN1POLBPHGDH | |
| SCHEMBL6780801 | 0.86 | MAPT (0.47) | KMT2AMEN1POLBPHGDHALDH1A1 | |
| SCHEMBL6965032 | 0.86 | PHGDH (0.58) | KMT2AMEN1POLBPHGDHALDH1A1 | |
| SCHEMBL6651512 | 0.77 | PHGDH (0.52) | KMT2AMEN1POLBPHGDHALDH1A1 | |
| SCHEMBL6961546 | 0.76 | KDM4E (0.48) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL6560454 | 0.75 | PHGDH (0.46) | KMT2AMEN1POLBPHGDHALDH1A1 | |
| SCHEMBL6652797 | 0.75 | PHGDH (0.55) | KMT2AMEN1POLBPHGDHGAA | |
| SCHEMBL6958779 | 0.75 | RBP4 (0.49) | KMT2APOLBALDH1A1GAAKDM4E | |
| SCHEMBL6651805 | 0.74 | CYP3A4 (0.47) | KMT2AMEN1POLBPHGDHALDH1A1 | |
| SCHEMBL6960450 | 0.74 | KDM4E (0.49) | KMT2APOLBALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |