Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960143 | 0.89 | KMT2A (0.48) | PHGDHMEN1KMT2APOLB | |
| SCHEMBL6965032 | 0.88 | PHGDH (0.58) | PHGDHMEN1KMT2APOLBPKM | |
| SCHEMBL6651512 | 0.87 | PHGDH (0.52) | PHGDHMEN1KMT2APOLBPKM | |
| SCHEMBL6961546 | 0.86 | KDM4E (0.48) | MEN1KMT2APOLBPKMCYP3A4 | |
| SCHEMBL6652797 | 0.77 | PHGDH (0.55) | PHGDHMEN1KMT2APOLBPKM | |
| SCHEMBL6958779 | 0.76 | RBP4 (0.49) | KMT2APOLBPKM | |
| SCHEMBL6562659 | 0.76 | PHGDH (0.54) | PHGDHMEN1KMT2APOLBPKM | |
| SCHEMBL6780801 | 0.75 | MAPT (0.47) | PHGDHMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL6960635 | 0.75 | PHGDH (0.54) | PHGDHMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL6956583 | 0.75 | KMT2A (0.53) | PHGDHKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |