Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972133 | 0.77 | MAPT (0.46) | PLK1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6972135 | 0.74 | MEN1 (0.47) | PLK1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6964973 | 0.72 | PLK1 (0.40) | PLK1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6964975 | 0.70 | PLK1 (0.42) | PLK1ALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL23558108 | 0.67 | SMN1; SMN2 (0.59) | PLK1ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4239653 | 0.65 | AR (0.54) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20037217 | 0.65 | MEN1 (0.60) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31338927 | 0.65 | SLC6A2 (0.46) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3927383 | 0.64 | KDM4E (0.62) | PLK1ALDH1A1HTTNPSR1TSHR | |
| SCHEMBL20075148 | 0.64 | SLC34A1 (0.53) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |