Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964973 | 0.78 | PLK1 (0.40) | PLK1ALDH1A1NPSR1TP53TSHR | |
| SCHEMBL6964978 | 0.78 | NPC1 (0.42) | ALDH1A1NPSR1TP53TSHRHSD17B10 | |
| SCHEMBL6966662 | 0.72 | NPSR1 (0.44) | ALDH1A1NPSR1TP53TSHRHSD17B10 | |
| SCHEMBL6972133 | 0.71 | MAPT (0.46) | PLK1ALDH1A1NPSR1TP53TSHR | |
| SCHEMBL6960209 | 0.70 | PLK1 (0.48) | PLK1ALDH1A1NPSR1TP53TSHR | |
| SCHEMBL1990381 | 0.68 | PTGS1 (0.54) | ALDH1A1HSD17B10LMNAGPR139KDM4E | |
| SCHEMBL6970481 | 0.66 | MEN1 (0.39) | PLK1ALDH1A1NPSR1TP53TSHR | |
| SCHEMBL6965184 | 0.65 | MAPT (0.40) | NOTUMNPC1KMT2AMAPT | |
| SCHEMBL27655360 | 0.64 | TDP1 (0.53) | ALDH1A1NPSR1TSHRLMNAKDM4E | |
| SCHEMBL11253413 | 0.64 | TDP1 (0.53) | ALDH1A1NPSR1TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |