Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 2/20 | 0.46 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959349 | 0.80 | VNN1 (0.47) | VNN1ALDH1A1NTRK1NTRK3NTRK2 | |
| SCHEMBL20037230 | 0.78 | KLK6 (0.76) | KLK6 | |
| SCHEMBL6969995 | 0.78 | ACP1 (0.45) | MEN1KMT2AVNN1ALDH1A1LMNA | |
| SCHEMBL6960209 | 0.74 | PLK1 (0.48) | MEN1KMT2APLK1ALDH1A1LMNA | |
| SCHEMBL6959537 | 0.74 | VNN1 (0.48) | MEN1KMT2AVNN1ALDH1A1LMNA | |
| SCHEMBL6960930 | 0.73 | VNN1 (0.47) | MEN1KMT2AVNN1ALDH1A1LMNA | |
| SCHEMBL6970481 | 0.73 | MEN1 (0.39) | MEN1KMT2AVNN1PLK1ALDH1A1 | |
| SCHEMBL6966662 | 0.73 | NPSR1 (0.44) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL6959326 | 0.72 | VNN1 (0.51) | VNN1ALDH1A1LMNANTRK1NTRK3 | |
| SCHEMBL8559433 | 0.71 | LRRK2 (0.46) | MEN1KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |