Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966662 | 0.76 | NPSR1 (0.44) | GRM5ALDH1A1LMNATP53TSHR | |
| SCHEMBL6960209 | 0.72 | PLK1 (0.48) | PLK1GRM5ALDH1A1LMNATP53 | |
| SCHEMBL6972133 | 0.71 | MAPT (0.46) | PLK1GRM5ALDH1A1LMNATP53 | |
| SCHEMBL6964978 | 0.70 | NPC1 (0.42) | GRM5ALDH1A1LMNATP53TSHR | |
| SCHEMBL6970481 | 0.68 | MEN1 (0.39) | PLK1GRM5ALDH1A1LMNATP53 | |
| SCHEMBL6965184 | 0.65 | MAPT (0.40) | NOTUMUBE2MDCUN1D1KMT2AMEN1 | |
| SCHEMBL6964956 | 0.64 | L3MBTL1 (0.47) | ALDH1A1LMNATSHRNPSR1KMT2A | |
| SCHEMBL4239759 | 0.64 | SLC34A1 (0.51) | NPSR1KMT2AMEN1POLBNR3C1 | |
| SCHEMBL3834637 | 0.64 | F11 (0.52) | PLK1GRM5ALDH1A1TP53TSHR | |
| SCHEMBL6972370 | 0.63 | S1PR1 (0.36) | PLK1ALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |