Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953373 | 0.87 | MEN1 (0.41) | MEN1KMT2AHTTSLC6A3SLC6A2 | |
| SCHEMBL6954026 | 0.87 | SLC18A3 (0.51) | MEN1KMT2AHTTNPC1TP53 | |
| SCHEMBL6952186 | 0.86 | SLC6A3 (0.40) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6959529 | 0.86 | KMT2A (0.40) | MEN1KMT2AHTTSLC6A3SLC6A2 | |
| SCHEMBL6955374 | 0.84 | MEN1 (0.41) | MEN1KMT2AHTT | |
| SCHEMBL6949144 | 0.83 | GPR119 (0.39) | MEN1KMT2AHTTNPC1TP53 | |
| SCHEMBL7076465 | 0.80 | HRH3 (0.45) | MEN1KMT2A | |
| SCHEMBL7084816 | 0.79 | CA12 (0.46) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6952629 | 0.79 | MEN1 (0.35) | MEN1KMT2AHTTTSHRSMN1; SMN2 | |
| SCHEMBL6947646 | 0.79 | MEN1 (0.42) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |