Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080534 | 0.87 | HRH3 (0.42) | HRH3CYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL6042500 | 0.85 | CYP4F2 (0.47) | HRH3CYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL6955374 | 0.81 | MEN1 (0.41) | HRH3MEN1KMT2A | |
| SCHEMBL6960338 | 0.80 | MEN1 (0.43) | MEN1KMT2A | |
| SCHEMBL7084816 | 0.80 | CA12 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6953373 | 0.76 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL6954026 | 0.76 | SLC18A3 (0.51) | HRH3MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL6959529 | 0.75 | KMT2A (0.40) | HRH3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6952186 | 0.75 | SLC6A3 (0.40) | HRH3MEN1KMT2AATM | |
| SCHEMBL7077994 | 0.75 | SLC6A1 (0.41) | MEN1KMT2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |