Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.53 |
| ▸ | KIT | P10721 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959104 | 0.89 | TRPV1 (0.52) | TRPV1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL6966521 | 0.85 | METAP1 (0.57) | TRPV1LMNAKDM4EALDH1A1GAA | |
| SCHEMBL6783151 | 0.74 | RBP4 (0.60) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL6960617 | 0.74 | KMT2A (0.53) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL6956583 | 0.74 | KMT2A (0.53) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL6559685 | 0.72 | MAPT (0.50) | TRPV1LMNAALDH1A1GAAKMT2A | |
| SCHEMBL6882152 | 0.71 | ALDH1A1 (0.59) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL5788028 | 0.71 | ALDH1A1 (0.52) | LMNAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL15452447 | 0.69 | CYP3A4 (0.84) | ALDH1A1KMT2AMEN1MAPTCYP2C9 | |
| SCHEMBL28206921 | 0.69 | KDM4E (0.92) | TRPV1LMNAKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |