Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960683 | 0.89 | TRPV1 (0.53) | TRPV1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6966521 | 0.74 | METAP1 (0.57) | TRPV1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL6961546 | 0.74 | KDM4E (0.48) | LMNAALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3598140 | 0.71 | PKM (0.56) | PKM | |
| SCHEMBL6966930 | 0.71 | KMT2A (0.47) | TRPV1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL6782052 | 0.70 | RBP4 (0.58) | TRPV1LMNAALDH1A1KMT2AGAA | |
| SCHEMBL3588436 | 0.70 | PKM (0.59) | PKM | |
| SCHEMBL7623427 | 0.69 | MAPT (0.44) | TRPV1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL3269610 | 0.69 | FAAH (0.60) | TRPV1KMT2AMEN1HTTCYP2C9 | |
| SCHEMBL20014197 | 0.69 | CYP2C9 (0.75) | LMNAALDH1A1KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |