Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074672 | 0.88 | MDM2 (0.33) | MEN1KMT2AMC4RGAA | |
| SCHEMBL6958920 | 0.85 | MDM2 (0.34) | SLC6A4SLC6A3TRPV1 | |
| SCHEMBL6951399 | 0.81 | SLC6A3 (0.37) | KMT2ARIPK1SLC6A3 | |
| SCHEMBL6955257 | 0.78 | MIF (0.35) | PDE5A | |
| SCHEMBL7073808 | 0.77 | GPBAR1 (0.41) | MEN1KMT2AMC4R | |
| SCHEMBL6041482 | 0.76 | MDM2 (0.36) | TRPV1NFKB1NFKB2RELA | |
| SCHEMBL6958285 | 0.76 | — | — | |
| SCHEMBL6951574 | 0.74 | TACR1 (0.37) | SLC6A4SLC6A3 | |
| SCHEMBL6959116 | 0.73 | RORC (0.35) | — | |
| SCHEMBL6042862 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2ASLC6A4SLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |