Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964414 | 0.89 | HPGD (0.38) | TYMSLMNA | |
| SCHEMBL6961409 | 0.86 | DHFR (0.30) | TYMSXPO1 | |
| SCHEMBL6961662 | 0.86 | TYMS (0.31) | TYMSLMNASMN1; SMN2 | |
| SCHEMBL6967036 | 0.83 | LMNA (0.38) | LMNASMN1; SMN2 | |
| SCHEMBL6973863 | 0.81 | CDC7 (0.32) | LMNA | |
| SCHEMBL6973994 | 0.81 | TYMS (0.31) | TYMSXPO1 | |
| SCHEMBL6973475 | 0.81 | CDK4 (0.37) | TYMS | |
| SCHEMBL6969886 | 0.80 | HSP90B1 (0.30) | — | |
| SCHEMBL6973128 | 0.80 | TYMS (0.35) | TYMSLMNASMN1; SMN2XPO1 | |
| SCHEMBL7084364 | 0.78 | HSP90B1 (0.32) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |