Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 5/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972380 | 0.80 | MMP3 (0.50) | PTGDRUSP5MMP3MMP2MMP1 | |
| SCHEMBL6433458 | 0.79 | PDE4B (0.43) | TLR8TLR7KMT2AMEN1ALDH1A1 | |
| SCHEMBL7204028 | 0.75 | MAPT (0.38) | PTGDRUSP5MMP3MMP2KMT2A | |
| SCHEMBL6966720 | 0.75 | MAPT (0.36) | PTGDRUSP5MMP3MMP2KMT2A | |
| SCHEMBL6966717 | 0.75 | MAPT (0.36) | PTGDRUSP5MMP3MMP2KMT2A | |
| SCHEMBL6966714 | 0.75 | MAPT (0.36) | PTGDRUSP5MMP3MMP2KMT2A | |
| SCHEMBL7204026 | 0.75 | KMT2A (0.38) | PTGDRMMP3MMP2KMT2AMAPT | |
| SCHEMBL6434485 | 0.74 | MMP3 (0.47) | USP5MMP3MMP2KMT2AMAPT | |
| SCHEMBL6437658 | 0.74 | MMP2 (0.51) | USP5MMP3MMP2KMT2AMAPT | |
| SCHEMBL6435225 | 0.72 | MMP3 (0.38) | USP5MMP3MMP2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |