SCHEMBL7204026

SCHEMBL7204026

Cc1cc(C2CCN(S(=O)(=O)OC(=O)[C@@H]3C[C@@H](O)[C@@H](O)C3)CC2)ccc1Br

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.37
MMP2 P08253 6/20 0.36
MMP3 P08254 6/20 0.36
MAPT P10636 2/20 0.36
MMP1 P03956 2/20 0.36
MMP9 P14780 2/20 0.36
MMP14 P50281 2/20 0.36
PTGDR Q13258 1/20 0.35
CHRNA3 P32297 1/20 0.35
GFER P55789 1/20 0.35
HTT P42858 1/20 0.34
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433458 0.76 PDE4B (0.43) KMT2AHTT
SCHEMBL6961774 0.75 PTGDR (0.39) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6437561 0.74 MMP3 (0.38) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6438533 0.74 MMP3 (0.38) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6966714 0.74 MAPT (0.36) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6966717 0.74 MAPT (0.36) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6966720 0.74 MAPT (0.36) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6972380 0.74 MMP3 (0.50) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6434485 0.73 MMP3 (0.47) KMT2AMMP2MMP3MAPTMMP1
SCHEMBL6437658 0.72 MMP2 (0.51) KMT2AMMP2MMP3MAPTMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199440-A1 Composition for the treatment of damaged tissue PFIZER INC. 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199440-A1 Composition for the treatment of damaged tissue MMP1, SERPINE1, COL14A1 KMT2A 4810/4885GAA 1575/4885MMP2 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.