Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MARK3 | P27448 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967118 | 0.94 | KCNH3 (0.36) | KCNH3POLBPDGFRBPDGFRAKMT2A | |
| SCHEMBL6963615 | 0.87 | KMT2A (0.35) | PDGFRBPDGFRAKMT2AMEN1BLM | |
| SCHEMBL6962677 | 0.86 | SLC2A1 (0.40) | KCNH3PDGFRBPDGFRAKMT2ANPSR1 | |
| SCHEMBL6960659 | 0.85 | POLB (0.38) | KCNH3POLBPDGFRBPDGFRAKMT2A | |
| SCHEMBL6966508 | 0.85 | KMT2A (0.37) | KCNH3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL6955926 | 0.85 | P2RX3 (0.34) | PDGFRBPDGFRAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6963612 | 0.85 | KMT2A (0.35) | KCNH3PDGFRBPDGFRAKMT2ASMN1; SMN2 | |
| Thiophene SCHEMBL6961908 | 0.85 | KMT2A (0.34) | KCNH3PDGFRBPDGFRAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6960858 | 0.84 | ATM (0.35) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL6955632 | 0.83 | EGFR (0.33) | KCNH3KMT2ACDK2TP53EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |