Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.66 |
| ▸ | TTR | P02766 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CBR1 | P16152 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765702 | 0.84 | CXCL8 (0.64) | CHRM1SLC6A2SLC6A3SLC6A4HPGD | |
| SCHEMBL11614117 | 0.84 | CYP1A2 (0.57) | CHRM1SLC6A2SLC6A3SLC6A4MAPT | |
| SCHEMBL6958628 | 0.83 | SLC6A2 (0.66) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| Fenclofenac SCHEMBL25161 | 0.81 | CHRM1 (1.00) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| Fenclofenac SCHEMBL28279765 | 0.81 | CHRM1 (1.00) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| Fenclofenac SCHEMBL29438086 | 0.81 | CHRM1 (1.00) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| Fenclofenac SCHEMBL30509659 | 0.81 | CHRM1 (1.00) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| Fenclofenac SCHEMBL9692633 | 0.80 | CHRM1 (0.97) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| SCHEMBL12608893 | 0.80 | CHRM1 (0.77) | CHRM1SLC6A2SLC6A3SLC6A4TTR | |
| SCHEMBL5950358 | 0.80 | SLC6A2 (0.50) | CHRM1SLC6A2SLC6A3SLC6A4CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610721-B2 | Imidazo heterocyclic compounds | NOVO NORDISK A/S (DK) | 2003-08-26 | — | — | US | disclosed |
| EP-1268483-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| US-20010049385-A1 | Imidazo heterocyclic compounds | HIGH POINT PHARMACEUTICALS, LLC | 2001-12-06 | — | — | US | disclosed |
| WO-2001068651-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049385-A1 | Imidazo heterocyclic compounds | HRH4, HRH3, HRH2 | CHRM1 89/4885SLC6A2 1098/4885SLC6A3 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.