Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.64 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203132 | 0.86 | SLC6A1 (0.61) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| SCHEMBL6963416 | 0.84 | CHRM1 (0.58) | DRD2DRD3CHRM5ADRA1DADRA1A | |
| SCHEMBL6966810 | 0.84 | DRD2 (0.75) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| Hydrochloric Acid SCHEMBL6969678 | 0.83 | DRD2 (0.74) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| SCHEMBL7465752 | 0.81 | CHRM1 (0.51) | DRD2HRH1HTR2ACHRM5ADRA1A | |
| SCHEMBL11686598 | 0.81 | KDM1A (0.67) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| SCHEMBL11686604 | 0.81 | KDM1A (0.64) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| Hydrochloric Acid SCHEMBL11688573 | 0.80 | KDM1A (0.62) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| Hydrochloric Acid SCHEMBL11688568 | 0.80 | KDM1A (0.66) | KDM1ADRD2HRH1DRD3SLC6A2 | |
| SCHEMBL9084388 | 0.78 | SLC6A1 (0.74) | SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934313-B1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-05-14 | — | — | EP | claimed |