Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 14/20 | 0.51 |
| ▸ | DRD2 | P14416 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464940 | 0.85 | CHRM1 (0.55) | CHRM1DRD2KCNH2HTR2AMCHR1 | |
| Hydrochloric Acid SCHEMBL7470371 | 0.84 | CHRM1 (0.54) | CHRM1DRD2KCNH2HTR2AMCHR1 | |
| SCHEMBL6963416 | 0.82 | CHRM1 (0.58) | CHRM1DRD2CHRM2CHRM4CHRM5 | |
| SCHEMBL6962033 | 0.81 | KDM1A (0.64) | CHRM1DRD2KCNH2HTR2ACHRM2 | |
| SCHEMBL7472521 | 0.80 | CHRM5 (0.41) | CHRM1DRD2HTR2AMCHR1CHRM5 | |
| SCHEMBL7466060 | 0.79 | ALDH1A1 (0.53) | CHRM1KCNH2 | |
| SCHEMBL8201840 | 0.78 | SLC6A1 (0.48) | CHRM1DRD2KCNH2HTR2AMCHR1 | |
| SCHEMBL8203622 | 0.78 | CHRNB2 (0.47) | — | |
| SCHEMBL7468275 | 0.76 | DRD2 (0.63) | CHRM1DRD2KCNH2HTR2AMCHR1 | |
| SCHEMBL7473583 | 0.76 | SIGMAR1 (0.43) | CHRM3HRH1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851865-B1 | 12H-Dibenzo[d,g][1,3]dioxocine derivatives | NOVO NORDISK AS (DK) | 2002-07-17 | — | — | EP | claimed |