Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.50 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.50 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28685608 | 0.98 | GABRA5 (0.48) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL355219 | 0.88 | CPN1 (0.44) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL10512591 | 0.86 | GABRA5 (0.50) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27891333 | 0.81 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL29252688 | 0.81 | GABRA5 (0.42) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| Glycinebetaine SCHEMBL11167590 | 0.81 | SLC6A1 (0.39) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| Hydrochloric Acid SCHEMBL6199423 | 0.79 | INPP5A (0.48) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL31207909 | 0.79 | GABRA5 (0.43) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL1081079 | 0.78 | GABRA5 (0.45) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 | |
| SCHEMBL20754591 | 0.78 | GABRA5 (0.45) | GABRA5SLC6A1GABRB2SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591212-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-114591212-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1060178-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045006-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| US-4877885-A | Novel 3-sulfinatomethyl-or 3-sulfonatomethyl-4-sulfomethyl pyrrolidinium betaines and their salts as well as process for making the same | AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) | 1989-10-31 | — | — | US | disclosed |